It seems obvious that psychotherapy must have an impact on brain processes, considering the extent of the brain's inherent plasticity. But how does psychotherapy change the brain and what do therapists do--or what should they do--to be more effective in bringing these changes about? In this workshop, we'll discuss the psychological conditions of therapy that promote neurobiological change: how a safe therapeutic relationship creates the neurobiological context necessary for change, how clinically controlled states of cognitive and emotional arousal lead to neural protein synthesis, and how therapeutic narratives seem to develop new neural circuits. You'll learn the ways in which the language and metaphors of different models of therapy tap into different brain processes, and what our current state of neurological knowledge suggests about how to have a direct impact on particular brain functions. (This session will continue with Workshop 302.)